Two sample MR report
ELP5_Alveolar Macrophages against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 8 | -0.0587258 | 0.1484859 | 0.7061545 |
| Weighted median | 8 | 0.0393370 | 0.0112084 | 0.0004488 |
| Inverse variance weighted | 8 | 0.0402657 | 0.0091304 | 0.0000103 |
| Simple mode | 8 | 0.0395661 | 0.0157382 | 0.0401601 |
| Weighted mode | 8 | 0.0387911 | 0.0158070 | 0.0438469 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1930624 | 6 | 0.9998605 |
| Inverse variance weighted | 0.6392025 | 7 | 0.9987605 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0652727 | 0.0977228 | 0.5290145 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001143 | 0 | TRUE | 0.3116338 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
